Perinatal Mental Health
PHQ-9 Perinatal Depression Screen
9-item depression screen for pregnancy and postpartum. PHQ-9 vs EPDS, score interpretation, when to seek urgent help, treatment options (CBT, antidepressants), how to support partners. NICE NG192.
Last reviewed 2 June 2026
Over the last 2 weeks, how often have you been bothered by…
Am I depressed or just exhausted?
Both are real and can overlap.
Normal tiredness: exists alongside baseline ability to enjoy moments, feel some warmth toward baby/partner; emotions vary day-to-day.
Depression: persistent low mood + loss of interest/pleasure MOST OF THE DAY, NEARLY EVERY DAY, for 2+ weeks. Often with guilt, hopelessness, self-harm thoughts.
NOT “baby blues” (which resolves in 2 weeks).
PHQ-9 vs EPDS
- EPDS (Edinburgh Postnatal Depression Scale): 10 items; excludes physical symptoms (sleep, fatigue) to avoid false positives in new mothers. Designed for perinatal. UK favourite.
- PHQ-9: 9 items mapped to DSM-5 MDD criteria; includes physical symptoms. Wider validation. US favourite. USPSTF-endorsed.
Either acceptable. Use whichever your service offers.
How common is PND?
~10-15% of new mothers (some studies up to 20%). Risk higher if: previous depression, family history, traumatic birth, NICU baby, lack of support, financial stress, partner strain, sleep deprivation, fertility journey trauma.
Also affects ~10% of new dads. Recognise and screen partners too.
PHQ-9 score interpretation
- 0-4: minimal / not depression.
- 5-9: mild.
- 10-14: moderate.
- 15-19: moderately severe.
- 20-27: severe.
Any active thoughts of self-harm (item 9): URGENT review.
≥10: likely depression, GP referral.
≥15: moderate-severe, urgent referral, consider antidepressants.
Postpartum psychosis — emergency
Rare (~1 in 1,000) but EMERGENCY. Symptoms within first 2 weeks postpartum: confusion, paranoia, hallucinations, delusions, severe mood swings, mania, insomnia.
Higher risk: previous psychosis, bipolar disorder, family history. Call 999 / 111 / perinatal mental health team immediately.
When to be screened
- Booking (first midwife appointment).
- 28 weeks pregnancy.
- 6-8 weeks postpartum (6-week check).
- 3-4 months postpartum.
- Whenever concerned.
Treatment options
- Talking therapy — CBT, IPT. NHS Talking Therapies free. NICE first-line for mild-moderate.
- Antidepressants — SSRIs (sertraline first-line in pregnancy + breastfeeding). Risks vs benefits weighed.
- Social support — peer groups (Pandas Foundation, NCT).
- Self-care — sleep, eat, light, gentle movement.
- Partner + family involvement.
- Perinatal mental health team for severe cases.
Antidepressants in pregnancy / breastfeeding?
Untreated depression has REAL risks: growth issues, preterm birth, attachment problems.
SSRI risks in pregnancy: small. Sertraline first choice (lowest milk transfer). Risks of NOT treating typically outweigh risks of treating.
Shared decision with mental health team. WHO advice: continue established treatment in pregnancy unless safer alternative available.
Self-harm thoughts — urgent help
- Don’t be alone — call partner, family, friend.
- NHS 111 in UK or 988 / 911 in US.
- Perinatal mental health crisis line (varies by area).
- GP same-day or A&E.
Postpartum psychosis is a medical emergency. PND with suicidal thoughts is also emergency.
Intrusive thoughts (unwanted thoughts of harming baby in OCD-like manner) common in PND/anxiety; not the same as wanting to harm — speak to GP. You are NOT a bad mother for these thoughts.
Different scenarios — perinatal depression
Scenario 1: First-time mum, 8 weeks postpartum, exhausted + tearful
Could be baby blues (early) or PND. Health visitor screening. PHQ-9 + EPDS. Refer if ≥10. Support practical (sleep, partner help, support groups).
Scenario 2: Previous PND, planning second pregnancy
Preconception planning with GP. Consider preventive antidepressant 2nd-3rd trimester. Specialist perinatal mental health team referral. Birth plan includes mental health monitoring.
Scenario 3: 28 weeks pregnant, anxious + low mood
Antenatal PND / anxiety. PHQ-9 + GAD-7. CBT via NHS Talking Therapies free. SSRI if moderate-severe. Birth plan adaptations (partner support, less stimulating environment).
Scenario 4: Postpartum psychosis symptoms at day 5
Emergency. 999 / out-of-hours psychiatric service. Mother-and-baby unit admission usually. Excellent recovery rate with treatment.
Scenario 5: New dad struggling, withdrawn, irritable
Paternal PND. PHQ-9 screen. GP referral. CBT via Talking Therapies. Pandas Foundation peer support. Don’t overlook partner.
Care guidance — perinatal mental health
- Routine screening at booking, 28 wk, 6-8 wk postpartum.
- Tell midwife / GP / HV if struggling.
- Self-harm thoughts: urgent help — 111 / 999 / crisis line.
- Talking therapy first-line (NHS Talking Therapies free).
- Sertraline first-line SSRI in pregnancy + breastfeeding.
- Don’t stop established treatment without consultation.
- Screen partners — paternal PND ~10%.
- Previous PND: proactive plan for next pregnancy.
- Support charities: Pandas Foundation, Mind, Maternal Mental Health Alliance.
- NOT YOUR FAULT; treatment helps.
Sources
- NICE NG192. Antenatal and postnatal mental health.
- ACOG Clinical Practice Guideline No. 4 (2023). Screening and diagnosis of mental health conditions during pregnancy and postpartum.
- Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med 2001.
- Cox JL, Holden JM, Sagovsky R. Edinburgh Postnatal Depression Scale (EPDS). Br J Psychiatry 1987.
- NHS Maternal Mental Health Alliance. maternalmentalhealthalliance.org.
- Pandas Foundation. pandasfoundation.org.uk.
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